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Highly efficient methods for the one-pot synthesis of b-substituted enones

Kerr, W.J. and Pearson, C.M. and Thurston, G.J. (2006) Highly efficient methods for the one-pot synthesis of b-substituted enones. Organic and Biomolecular Chemistry, 4. pp. 47-50.

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Abstract

A mild and practically-convenient one-pot procedure for the direct b-substitution of enones has been developed using a conjugate addition–oxidation strategy with a full range of copper-based reagents and N-tert-butylphenylsulfinimidoyl chloride; alkyl- and aryl-substituted enones are delivered in good to excellent yields.